Aging and Brain Research

In a recent study led by researchers from the University of South Australia (UniSA), scientists have uncovered the profound impact of fluctuating blood pressure on the cognitive health of older individuals, shedding light on the connection between blood pressure variations and the risk of dementia and vascular issues in the elderly.  High blood pressure is well-known as a risk factor for dementia, but the study underscores the importance of addressing the often-overlooked issue of fluctuating blood pressure in clinical treatments. To understand the mechanisms connecting blood pressure fluctuations with dementia, the researchers recruited 70 healthy older adults, aged 60-80, without cognitive impairment. They carefully monitored participants' blood pressure, conducted cognitive tests, and employed specialized techniques to measure arterial stiffness in the brain and arteries. The study unveiled a striking revelation: higher blood pressure variability, whether within a single day or ...

Ageing is an intricate journey marked by the ebb and flow of physical and cognitive capacities. As we advance in years, our bodies and minds undergo transformations, both subtle and profound. However, the ageing process is not uniform across individuals, and some extraordinary people manage to defy the odds, living well into their 90s and beyond. These individuals, known as nonagenarians and centenarians, offer a unique window into the mysteries of healthy aging. Sardinia's Blue Zone is renowned for its extreme longevity and unique characteristics—historical, geographic, social, linguistic, and nutritional. Within this captivating context, authors of a new study administered the Cognitive Reserve Index questionnaire (CRIq) and the short cognitive Esame Neuropsicologico Breve-2 (ENB-2) to 67 participants, all aged between 90 and 105 years old.  The study's findings provide compelling evidence of the positive relationship between cognitive reserve and cognitive performance, even...